Herbs and herbal products are of paramount importance for human health. To beable to guarantee safety and quality, standards and testing methods are needed.Pharmacopoeias contain quality control protocols setting the standards which arethen required by governments. The quality traits are many, including the intrinsicvariables of medicinal plant, e.g. the levels of the active compounds, and the absenceof possibly natural occurring toxic compounds. On the other hand, many qualitytraits are related to agricultural conditions and practices, or to the harvesting andpost-harvest processing. With so many variables, quality control of the end productbecomes extremely complex, time consuming and costly. To ensure the quality ofmedicinal plants for human consumption quality management -the use of “goodpractices” at each step, from seed to final product- becomes a crucial aspect. In general, quality control includes the inspection of the product’s identity, purity,and content, based on its physical, chemical or biological properties. To ensure thequality of herbal medications, criteria such as botanical quality, type of preparation,physical constants, adulteration, contaminants, chemical constituents, pesticidesresidues et al. should be examined. Meanwhile, authentication of herbs is neededto avoid possible adulteration or contaminating plants, even toxic herbs such asAristolochia species. Many of the methods are long standing, such as microscopy incombination with color reactions, but some 50 years ago chromatography developedas a major tool for both qualitative and quantitative analysis of herbal preparations.Nowadays, research is working on the improvement of these methods and on thedevelopment of novel tools. For instance, next generation sequencing and mass spectrometry imaging, areemerging as new technologies for the quality control of herbal medicines. Withthese technologies, quick testing of herbal products and of mixed herbal powderpreparations, including the testing for specific plant parts (botanical drugs), can beachieved. Also, novel chemical tools such as metabolomics and Near Infrared Red(NIR) spectroscopy are being developed as powerful tools to identify and to linkthese with activity by using chemometric tools such as multivariate analysis. Finally,progress of informatic tools such as machine learning helps to deal with the big datagenerated by sequencing or mass spectrometry. However, these new technologies,like all other new born technologies, should be tested and perfected for a broaderrange of products.
The 2nd Universitas Kuningan International Conference on System, Engineering, and Technology (UNISET) will be an annual event hosted by Universitas Kuningan. This year (2021), will be the second UNISET will be held on 2 December 2021 at Universitas Kuningan, Kuningan, West Java, Indonesia. “Opportunity and challenge in environmental, social science and humanity research during the pandemic Covid-19 era and afterward” has been chosen at the main theme for the conference, with a focus on the latest research and trends, as well as future outlook of the field of Call for paper fields to be included in UNISET 2021 are: natural science, education, social science and humanity, environmental science, and technology. The conference invites delegates from across Indonesian and South East Asian region and beyond, and is usually attended by more than 100 participants from university academics, researchers, practitioners, and professionals across a wide range of industries.
Quality Control and Evaluation of Herbal Drugs brings together current thinking and practices for evaluation of natural products and traditional medicines. The use of herbal medicine in therapeutics is on the rise in both developed and developing countries and this book facilitates the necessary development of quality standards for these medicines.This book elucidates on various challenges and opportunities for quality evaluation of herbal drugs with several integrated approaches including metabolomics, chemoprofiling, marker analysis, stability testing, good practices for manufacturing, clinical aspects, Ethnopharmacology and Ethnomedicine inspired drug development. Written by Prof. Pulok K Mukherjee, a leader in this field; the book highlights on various methods, techniques and approaches for evaluating the purity, quality, safety and efficacy of herbal drugs. Particular attention is paid to methods that assess these drugs’ activity, the compounds responsible and their underlying mechanisms of action. The book describes the quality control parameters followed in India and other countries, including Japan, China, Bangladesh, and other Asian countries, as well as the regulatory profiles of the European Union and North America. This book will be useful in bio-prospecting of natural products and traditional medicine-inspired drug discovery and development. Provides new information on the research and development of natural remedies - essential reading on the study and use of natural resources for preventative or healing purposes Brings together current thinking and practices in quality control and standardization of herbal drugs highlighting several integrated approaches for metabolomics, chemo-profiling and marker analysis Aids in developing knowledge of various techniques including macroscopy, microscopy, HPTLC, HPLC, LC-MS/MS, GC-MS etc. with the development of integrated methods for evaluation of botanicals used in traditional medicine Assessment of herbal drugs through bio-analytical techniques, bioassay guided isolation, enzyme inhibition, pharmacological, microbiological, antiviral assays and safety related quality issues References global organizations, such as the WHO, USFDA, CDSCO, AYUSH, TCM and others to serve as a comprehensive document for enforcement agencies, NGOs and regulatory authorities
This new book, Plant- and Marine- Based Phytochemicals for Human Health: Attributes, Potential, and Use, provides insight with scientific evidence on the use of medicinal plants in the treatment of certain diseases. It describes bioactive compounds of marine and plant origin that have been discovered to be advantageous for human health, shedding new light on the potential of phytochemicals on human health and contributing to the ocean of knowledge on phytochemistry and pharmaceutical biology. In addition, the role of plant-based pharmaceuticals is also discussed as an example of innovative uses of plant product. This book addresses the importance of phytochemicals from plants and marine life. It divided in four parts: Bioactive compounds in medicinal plants: status and potential Plant-based pharmaceuticals in human health: review Therapeutic attributes of mushroom, cereal grains, and legumes Innovative use of medicinal plants This compendium will be useful for the students and researchers as well as for industry professionals working in the food, nutraceuticals, and herbal industries.
Traditional medicines, especially the folk herbal medicines have recently been receiving heightened interest the world over. This reference book contains 24 papers by eminent scientists on herbal drugs, drug discovery and other related topics which deal with biological activities and aspects of herbal drug research, such as anti-cancer, antidiabetic, anti-ischemic, anti-microbial, ethnomedicine, ethnopharmacology, pharmacognostic and phytochemistry.
Medicinal and aromatic plants (MAPs) have accompanied mankind from its very early beginnings. Their utilization has co-evolved with homo sapiens itself bringing about a profound increase in our scientific knowledge of these species enabling them to be used in many facets of our life (e.g. pharmaceutical products, feed- and food additives, cosmetics, etc.). Remarkably, despite the new renaissance of MAPs usage, ca. 80 % of the world’s population is relying on natural substances of plant origin, with most of these botanicals sourced from the wild state. This first volume and ultimately the series, provides readers with a wealth of information on medicinal and aromatic plants.
Medicines are the second most essential requisite after food for mankind. For medicines, medicinal plants are the important sources of raw drugs. Therefore, the demand on plant based therapeutics has increased many fold in both developing and developed countries due to the growing recognition that they are natural products, being non-narcotic, having no side effects, easily available at affordable prices. Due to hug demand of plant-based crude drugs throughout the world, today urgent need to domesticate or cultivate the medicinal plants in large scale to fulfill the unexpected demand. But due to lack of systematic information on cultivation of medicinal crops at one place, growers are not ready to adopt such practices in their agrosystem. Changing herbal market scenario rapidly and expanding local and global market and immense export potential to Europe, America and other Western Countries has opened up a new prospective field for Indian agriculture. To fully make use of this emerging demands world wide appropriate knowledge regarding their value addition, processing, market potential (export/import) of crude drugs, adulterants and substitutions and crude drugs and standardization and quality control is of utmost important. This unique book ventures to probe into this very important area covering almost the entire gamut of the burning issues relating to medicinal plants. The export of crude (herbal) drugs is gaining strength due to its inherent advantage coupled with the proliberalization. This invaluable book consisting of 11 chapters contributed every aspects related to the cultivation of medicinal plants viz. Nursery technology, Biofertilizers and biological pest control, Organic farming, Agro technique (40 commercial important medicinal plants), Harvesting technology and value addiction, Adulterants and substitutions, Market potential (export/import), Standardization and quality control, Legistration and policy, Sustainable conservation and development strategies. This book is a ready manual and information database for policy makers, administrators, academia, exporters, extension workers, manufacturers, growers and general readers interested in medicinal plants.
Medicinal Spices and Vegetables from Africa: Therapeutic Potential against Metabolic, Inflammatory, Infectious and Systemic Diseases provides a detailed look at medicinal spices and vegetables that have proven safe-and-effective for consumption and the treatment of diseases, including infectious diseases, cardiovascular disease, and cancer. It provides pharmacological evidence, such as the latest information related to efficacy and safety data, in vitro and in vivo studies, clinical trials, and more, to illustrate the use of these spices and vegetables as both palliative and alternative treatments with the goal of furthering research in this area to produce safer and more effective drugs. Provides scientific evidence for the potential of medicinal spices and vegetables used in Africa to fight metabolic, inflammatory, and infectious diseases Includes a review of the latest methods used to investigate the effects of medicinal plants in the treatment of disease Offers an updated resource for students sand scientists in the fields of pharmaceutical science, pharmacognosy, complementary and alternative medicine, ethnopharmacology, phytochemistry, biochemistry, and more
Evidence-Based Validation of Herbal Medicines: Translational Research on Botanicals brings together current thinking and practice in the characterization and validation of natural products. The book describes different approaches and techniques for evaluating the quality, safety and efficacy of herbal medicine, particularly methods to assess their activity and understand compounds responsible and their probable underlying mechanisms of action. This book brings together the views, expertise and experiences of scientific experts in the field of medicinal plant research, hence it will be useful for researcher who want to know more about the natural lead with their validation and also useful to exploit traditional medicines. Includes state-of-the-art methods for detecting, isolating and performing structure elucidation by degradation and spectroscopic techniques Highlights the trends in validation and value addition of herbal medicine with different scientific approaches used in therapeutics Contains several all-new chapters on topics such as traditional-medicine-inspired drug development to treat emerging viral diseases, medicinal plants in antimicrobial resistance, TLC bio profiling, botanicals as medicinal foods, bioprospecting and bioassay-guided isolation of medicinal plants, immunomodulators from medicinal plants, and more
Phytochemicals from Medicinal Plants: Scope, Applications and Potential Health Claims explores the importance of medicinal plants and their potential benefits for human health. This book looks at bioactive compounds from medicinal plants, the health benefits of bioactive compounds, the applications of plant-based products in the food and pharmaceutical industries. The first section discusses available sources of bioactive compounds from medicinal plants, biochemistry, structural composition, potential biological activities, and how bioactive molecules are isolated from medicinal plants. The authors examine the applications of bioactive molecules from a health perspective, looking at the pharmacological aspects of medicinal plants, the phytochemical and biological activities of different natural products, and ethnobotany/and medicinal properties, and also present a novel dietary approach for disease management. The book goes on to examine the plant-based products are used and can be used in various sectors of the food and pharmaceutical industries.
This is the newest title in the successful Molecular Plant Biology Handbook Series. Just like the other titles in the series this new book presents an excellent overview of different approaches and techniques in Metabolomics. Contributors are either from ivy-league research institutions or from companies developing new technologies in this dynamic and fast-growing field. With its approach to introduce current techniques in plant metabolomics to a wider audience and with many labs and companies considering to introduce metabolomics for their research, the title meets a growing market. The Kahl books are in addition a trusted brand for the plant science community and have always sold above expectations.
Designed to cover the core subject of pharmacognosy offered to undergraduate students of pharmacy, this book presents the theoretical concepts in a lucid style. Its in-depth coverage of topics quintessential to the Indian plant drug sector makes the book unique, as does its exposition on herbal cosmetics and quality control of herbal drugs. The book abounds with a rich pedagogy that enables effortless recapitulation of the subject.